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Case Fatality Rate

Also Known As Case-Fatality Risk
Epidemiology

The case fatality rate (CFR), sometimes called more precisely the case-fatality risk, is the proportion of people diagnosed with a disease who go on to die of it. It is easy to confuse with the mortality rate, but the two answer different questions: the mortality rate measures deaths, from any or a specific cause, against the whole population over a period of time, while the CFR measures deaths only among people already diagnosed with the disease, independent of time or the size of the general population. The measure varies enormously by disease: the 1918 Spanish influenza pandemic carried a CFR above 2.5 percent, while rabies is fatal in more than 99 percent of unvaccinated people who develop symptoms. This description is adapted from Wikipedia contributors under CC BY-SA 4.0; changes were made. https://creativecommons.org/licenses/by-sa/4.0/

Facts
Concept ClassSourced to the subject's own account
Epidemiological Measure 1
FAQs

Is the case fatality rate the same thing as the death rate?

No, and the two are commonly confused. The case fatality rate is the share of people already diagnosed with a specific disease who go on to die of it, so it says how dangerous a disease is once you have it. The (population) mortality rate is the share of an entire population, sick or not, that dies over a period of time, so it says how much death a disease is causing across society as a whole, which also depends on how many people actually catch it.
Connections

Associated With

Attack Rate, Concepts

Both are standard outbreak-investigation measures, tracking how many people are affected versus how many affected people die.

In Branch

Epidemiology, Branches

Open Questions

Sources
1. Wikipedia: Case Fatality Rate
Wikipedia
  • Lead section
    In epidemiology, case fatality rate (CFR), or sometimes more accurately case-fatality risk, is the proportion of people who have been diagnosed with a certain disease and end up dying of it.
  • Examples section, Spanish flu
    The CFR for the Spanish (1918) flu was greater than 2.5%
  • Examples section, Rabies
    Rabies has a CFR greater than 99% in unvaccinated individuals
  • Terminology section
    The mortality rate - often confused with the CFR - is a measure of the relative number of deaths (either in general, or due to a specific cause) within the entire population per unit of time. A CFR, in contrast, is the number of deaths among the number of diagnosed cases only, regardless of time or total population.
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Open Questions (1 open question)
What year did the case fatality rate originate as a named epidemiological measure?

The Wikipedia article on case fatality rate cited on this entity defines the measure, distinguishes it from the population mortality rate, and gives historical examples such as the 1918 influenza pandemic and rabies, but names no first use, no originating publication and no individual credited with introducing the term or the name case fatality rate.

What would resolve this A source tracing the term case fatality rate to a specific epidemiological publication and naming when it entered standard use, or a scholarly consensus that the term developed gradually with no single point of origin.
History of epidemiologyWikipedia: Case Fatality Rate
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