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Specificity (Screening and Diagnostic Testing)

Also Known As True Negative Rate
Preventive Care

Specificity is the probability that a screening or diagnostic test returns a negative result, conditioned on the person truly not having the condition being tested for: a highly specific test rarely flags a healthy person as positive, making it useful for confirming a condition when it comes back positive. It is sensitivity's counterpart, and the two are read together rather than alone, since prevalence in the tested population changes how a given sensitivity and specificity translate into the chance that a positive or negative result is actually correct. This description is adapted from Wikipedia contributors under CC BY-SA 4.0; changes were made. https://creativecommons.org/licenses/by-sa/4.0/

Facts
First Described YearSourced to the subject's own account
1947 1
First Described EraSourced to the subject's own account
1947, introduced by biostatistician Jacob Yerushalmy alongside sensitivity as a statistical measure of diagnostic test accuracy; comparable assessments of test accuracy trace back to early 1900s serology work on complement fixation testing for syphilis, before these two terms existed. 1
Concept ClassSourced to the subject's own account
Screening Test Measure 1
Connections

Associated With

Read together, never alone, as the two halves of a screening test's performance, in a documented trade-off with each other.

In Branch

Sources
1. Wikipedia: Sensitivity and Specificity
Wikipedia
  • Lead section
    Specificity (true negative rate) is the probability of a negative test result, conditioned on the individual truly being negative. If the true status of the condition cannot be known, sensitivity and specificity can be defined relative to a "gold standard test" which is assumed correct.
  • Misconceptions section
    prevalence rates significantly affect these interpretations
  • Article body, sentence on the 1947 introduction
    The terms "sensitivity" and "specificity" were introduced by American biostatistician Jacob Yerushalmy in 1947.
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