A specialized extension of the standard Directly Observed Treatment Short Course, or DOTS, tuberculosis strategy, built specifically to treat multidrug-resistant tuberculosis, a form of the disease that does not respond to the standard first-line drug regimen DOTS programs are built around. DOTS-Plus programs have proven a workable option for treating MDR-TB in poor, rural areas with limited health infrastructure, with the program in Lima, Peru cited as achieving cure rates exceeding 80 percent among patients enrolled. Implementation has not been uniform everywhere: in the country of Georgia, where the program relies on passive case-finding, meaning it waits for patients to seek care rather than actively screening for them, medical anthropologists studying the rollout identified cultural compatibility problems, concluding that MDR-TB treatment protocols need to be adapted to local practices, forms of knowledge and everyday life rather than applied as a uniform model everywhere they are introduced.
Facts
Sponsoring BodyWorld Health Organization 1 Target PopulationPatients with multidrug-resistant tuberculosis 1 Measured ResultsTreatment duration of 18 to 24 months total 1 Program status (class) Classification
Program Kind Connections
Sources
1. Tuberculosis management, Wikipedia
DOTS-Plus section
Management of tuberculosis refers to techniques and procedures utilized for treating tuberculosis (TB), or simply a treatment plan for TB. The medical standard for active TB is a short course treatment involving a combination of isoniazid, rifampicin (also known as Rifampin), pyrazinamide, and ethambutol for the first two months.
DOTS-Plus section, opening line
The WHO extended the DOTS programme in 1998 to include the treatment of MDR-TB (called DOTS-Plus)
DOTS-Plus treatment duration line
Treatment with the new strategy is a total duration of 18-24 months
DOTS-Plus section heading
called DOTS-Plus
Program classification, entity description sentence
Implementation has not been uniform everywhere: in the country of Georgia, where the program relies on passive case-finding, meaning it waits for patients to seek care rather than actively screening for them, medical anthropologists studying the rollout identified cultural compatibility problems, concluding that MDR-TB treatment protocols need to be adapted to local practices, forms of knowledge and everyday life rather than applied as a uniform model everywhere they are introduced.
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